Hormone Therapy Usage in Decline

In the past, Dr. Martin Appelt of the Canadian Food Inspection Agency promoted the  deadly Premarin®/Prempro® industry whilst referring to menopause as a “disease”  that requires treatment (apparently,  with Premarin®).  But as we know,  the opinions and views of the CFIA are often in direct antipathy with acknowledged science.

premarinThe Women’s Health Initiative was a long-term national health studied that focused on strategies for preventing cancer,  heart disease, and osteoporosis in post-menopausal women.  The study,  which produced over 1,000 articles and approved 340 ancillary studies,  changed the way that doctors treated and prescribed drugs for women.

About 18 per cent of Canadian women aged 50-69 were taking HRT drugs in 2002.  By 2004, after the U.S. government-funded WHI results were published, that rate had dropped to less than five per cent. The risks of HRT were made clear.  Last year we read that the class action lawsuit launched against Wyeth Canada Inc. for selling the once ubiquitous hormone replacement therapy drugs settled and a $13.65 million payment awarded by the B.C. Supreme Court.

In the U.S., Pfizer has paid out more than $1 billion in numerous other HRT  cases. Unfortunately, it is easy and comfortable for physicians to prescribe drugs that have been around for a long time. It is also easy not to think about our contribution to the cruel chain of events that our prescriptions may allow.  The industry continues to be heavily scrutinized for its impact on women and its production of horses in an already saturated market.    Premarin (1)

Two new articles have been published on the emerging deconstruction of the conjugated equine estrogen industry:

From The Spectrum,  written by Amey Vance

For almost six decades, doctors have prescribed hormone replacement therapies (HRT) to help women cope with symptoms. In the early 2000s, the Women’s Health Initiative conducted the first major clinical trial of the risks and benefits of estrogen and progestin and estrogen alone hormone replacement therapies.

“Initially, hormone replacement therapy was used to treat several conditions, said Derrick Haslem, oncologist with Intermountain Southwest Cancer Center, including osteoporosis, vaginal dryness, heart disease, mood swings, and post-menopausal symptoms.

The Women’s Health Initiative clinical trials of estrogen and progestin combined hormone replacement therapy and were stopped early when test results began to show a marked increase in the risk of breast cancer, coronary heart disease, and pulmonary embolism.

After the Women’s Health Initiative study, it became very clear that women over 60 should not take hormone replacement therapy for multiple reasons.”

Please also read this article from the Regulatory Affairs Professionals Society,  written by Nick Paul Taylor:

In the EU,  the EMA (European Medicines Agency) has updated the product information for hormone-replacement therapy (HRT). “The changes follow a review by the Pharmacovigilance Risk Assessment Committee (PRAC) late last year, which concluded EMA should strengthen the warning about the link between HRT and ovarian cancer.”

Dr. Ray Kellosalmi,, Retired Physician & Board Member of the Canadian Horse Defence Coalition, presented a talk at the 2014 American Equine Summit titled “Horse Slaughter & PMU: Shared Disgrace, Shared Challenge.”  This is a video of that talk.

For an in-depth look at the Premarin® industry please go here to read Jane Allin’s work on Premarin for the HorseFund.






  1. Pam Evely · ·

    Wouldn’;t matter even if premarin was good for women. It’s production is completely unethical and immoral, and should be outlawed based on it’s cruelty to horses. It’s not always about what humans think is good for them, but the damage we are doing to other species. And it usually turns out that what is bad for them is also bad for us, we’re just to stupid and egotistical to realize we’re being lied to by giant corporations, whether it’s pharmaceutical, agri-business, oil, or any other.Wake up human race, Karma is about to catch up to you, whether it’s by cancer or some other means. And no one can say we didn’t ask for it.

  2. Mary Croft · ·

    This entire industry is immoral….horrible for horses and women.

  3. I never used Premarin because I knew where it came from. The synthetic I used worked just fine for me.

  4. I think Pfizer has known all along what the dangers that their horse pee drug sold to women. They may have experimented using chimps to find out just what health problems it can cause. They have paid out billions in damages yet the FDA is still allowing it sold around the world. With the diseases that it causes being so common in the public that no one paid any attention to what was happening to the women that was taking some of these drugs for years. Take these drugs off of the market and you will see a dramatic drop in breast cancer as well as the other diseases that seem so common in the countries where it is sold. Breast cancer as far as I know never showed up in my grandmothers on both sides. That’s because Pfizer didn’t exist selling it. Breast cancer seems like a silent epidemic until you take a look at what might be causing a large portion of it.

  5. Lin Month · ·

    It is the horse pee estrogen that causes all these serious health problems. I take the plant based one and my health at 67 is more like that of a 35-year-old. Just had a medical with every test imaginable and no matter how hard they tried, they couldn’t find anything wrong with me.

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